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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPD2 All Species: 33.64
Human Site: Y628 Identified Species: 49.33
UniProt: P43304 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P43304 NP_000399.2 727 80853 Y628 L P S D I D R Y K K R F H K F
Chimpanzee Pan troglodytes XP_001142893 693 77234 A603 K R F H K F D A D Q K G F I T
Rhesus Macaque Macaca mulatta XP_001086947 727 80814 Y628 L P S D I D R Y K K R F H K F
Dog Lupus familis XP_848389 736 81958 Y637 L P S D I D R Y K K R F H K F
Cat Felis silvestris
Mouse Mus musculus Q64521 727 80935 Y628 L P S D I D R Y K K R F H K F
Rat Rattus norvegicus P35571 727 80954 Y628 L P P D I D R Y K K R F H M F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509091 727 80780 Y628 L P S D I D R Y K K R F H M F
Chicken Gallus gallus XP_422168 727 80733 Y628 M P S D I E R Y K K R F H M F
Frog Xenopus laevis NP_001086009 725 80597 Y626 S P S D V D R Y T K R F H K F
Zebra Danio Brachydanio rerio NP_001038813 536 58932 I451 E E T L D A A I K A H N L S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611063 724 80404 I623 K E E I Q T Y I K R F Q L I D
Honey Bee Apis mellifera XP_624293 720 80348 Y617 T K E E I Q L Y I K R F G I I
Nematode Worm Caenorhab. elegans P90795 722 80789 K630 K E E M Q R A K E R F Q Q L D
Sea Urchin Strong. purpuratus XP_782036 720 80442 T619 M T V P I N F T E G E K E K Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SS48 629 68433 F544 R L A H G H P F L E A E V A Y
Baker's Yeast Sacchar. cerevisiae P32191 649 72370 N564 V I Y S S E E N N L V N F D T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.3 99.1 91.9 N.A. 93.2 91.6 N.A. 90.5 82.9 82.8 61 N.A. 60.9 61.6 57.7 62.8
Protein Similarity: 100 95.3 99.7 94.2 N.A. 97.1 96.4 N.A. 95.7 92.4 91.3 67.4 N.A. 76.3 77.7 74.8 77.8
P-Site Identity: 100 0 100 100 N.A. 100 86.6 N.A. 93.3 80 80 6.6 N.A. 6.6 33.3 0 13.3
P-Site Similarity: 100 13.3 100 100 N.A. 100 86.6 N.A. 93.3 93.3 86.6 13.3 N.A. 13.3 40 13.3 40
Percent
Protein Identity: N.A. N.A. N.A. 41.4 29 N.A.
Protein Similarity: N.A. N.A. N.A. 54.8 46.2 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 7 13 7 0 7 7 0 0 7 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 50 7 44 7 0 7 0 0 0 0 7 13 % D
% Glu: 7 19 19 7 0 13 7 0 13 7 7 7 7 0 0 % E
% Phe: 0 0 7 0 0 7 7 7 0 0 13 57 13 0 50 % F
% Gly: 0 0 0 0 7 0 0 0 0 7 0 7 7 0 0 % G
% His: 0 0 0 13 0 7 0 0 0 0 7 0 50 0 0 % H
% Ile: 0 7 0 7 57 0 0 13 7 0 0 0 0 19 7 % I
% Lys: 19 7 0 0 7 0 0 7 57 57 7 7 0 38 0 % K
% Leu: 38 7 0 7 0 0 7 0 7 7 0 0 13 7 0 % L
% Met: 13 0 0 7 0 0 0 0 0 0 0 0 0 19 0 % M
% Asn: 0 0 0 0 0 7 0 7 7 0 0 13 0 0 0 % N
% Pro: 0 50 7 7 0 0 7 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 13 7 0 0 0 7 0 13 7 0 0 % Q
% Arg: 7 7 0 0 0 7 50 0 0 13 57 0 0 0 0 % R
% Ser: 7 0 44 7 7 0 0 0 0 0 0 0 0 7 0 % S
% Thr: 7 7 7 0 0 7 0 7 7 0 0 0 0 0 13 % T
% Val: 7 0 7 0 7 0 0 0 0 0 7 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 7 57 0 0 0 0 0 0 13 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _